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In these studies dietary arginine was found to be important for the maintenance of immune cell populations, for macrophage production of nitric oxide, for regulating inflammatory cytokines and for maintaining body weight through the challenge (Takahashi et al., 1999

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Given the many unknowns with high dose folic acid supplementation, particularly unmetabolized folic acid (as covered in my folate article), I’m not able to draw any strong conclusions here