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In that work dihexa was dissolved in DMSO at 1 mg/mL and serially diluted, with rats receiving roughly 200 microlitres of a vehicle that was up to 75 percent DMSO — approximately 150 microlitres of neat DMSO per dose, which against a total blood volume on the order of 25 to 30 millilitres for a rat of that size works out to roughly half a percent of blood volume (about 0.5 to 0.6 percent)

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Magnesium therapy in these individuals resulted in increases in both red blood cell magnesium and bone mineral density, suggesting magnesium deficiency may play a role in the development of osteoporosis in people with celiac disease (Rude 1996)