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Comparing DSIP to Proven Sleep Aids Context matters when evaluating any sleep intervention

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The GH-Sleep Bidirectional Relationship# The relationship between growth hormone and sleep is bidirectional: Sleep promotes GH -- the sleep-onset SWS period triggers the largest GH pulse of the day via GHRH release from the hypothalamus GH promotes sleep -- GHRH itself has been shown to promote SWS in human studies, creating a positive feedback loop Aging disrupts both -- age-related declines in GH secretion and SWS occur in parallel, suggesting a shared mechanism