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In contrast, a slightly delayed and less efficient host response allows limited virus replication and movement first resulting in oxidative stress and programmed cell death before conferring a final arrest of virus invasion (HR) (Bendahmane et al., GSTs and the Hypersensitive Type Resistance It has been known for decades that treatment of leaves with antioxidants like GSH decrease the number of HR-type necrotic lesions caused by virus infections but virus levels essentially remain the same (Farkas et al., N

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This finding suggests that targeting NRF2 could be a potential strategy for the prevention or treatment of CRC [159]