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It primarily affects the gastrointestinal and nervous systems of cats, leading to a wide range of symptoms such as fever, weight loss, loss of appetite, and neurological abnormalities

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The presence of purinosome potentially improves regulation of the metabolic flux and substrate channeling among enzymes in the pathway ( Extensive studies have been conducted on PurL from bacterial pathogens because it plays a vital role in supplying precursors for GMP and adenosine monophosphate (AMP)