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For example, oxidized cysteine (cystine) makes Salmonella enterica more sensitive to gentamicin by disrupting the intracellular redox balance, altered the GSH/GSSG ratio, raised ROS, and increased ferrous iron, which potentially fuels the Fenton reaction, all of which contribute to greater bactericidal activity

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Internal factors include the increasing need for glutathione as an important part of various processes in our bodies, such as food for our immune system, recycling of vitamin C, vitamin E and alpha lipoic acid, repairing our DNA, and protecting our cells from oxidative stress, etc