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Thus, structures of glutathionylated glutaredoxins 31,43,44,45 most likely resemble enzyme species ‘F’, whereas similar structures of complexes between reduced glutaredoxin and GSH with longer sulfur–sulfur distances 24,46 do not represent the interaction with GSH (but probably also resemble species ‘F’)

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PGE₂ mediates vasodilatation and hyperalgesia, while LTB₄ recruits polymorphonuclear leukocytes