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A matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) assay revealed several proteins with antioxidant functions including a GST that were differentially expressed between compatible and incompatible interactions, indicating the differential accumulation of ROS in infected tissues (Li et al., 2011)

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This is a significant gap that complicates dosing optimization and raises questions about long-term effects that cannot be fully answered yet

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